What question did this study set out to answer?

This research aims to evaluate the effects of high-dose induction therapy on feline infectious peritonitis and identify criteria for treatment termination.

March 18, 2026Open Access

EXPRESS: High-dose induction therapy and treatment termination criteria for feline infectious peritonitis with remdesivir and GS-441524

Key Points

This research aims to evaluate the effects of high-dose induction therapy on feline infectious peritonitis and identify criteria for treatment termination.
Administered high-dose induction therapy using remdesivir and GS-441524 to cats
Monitored SAA and α1AG concentrations during treatment
Assessed the outcomes of treatment cessation before 12 weeks
No clear adverse effects observed from high-dose induction therapy
Improvement in SAA and α1AG concentrations correlated with treatment termination
Further studies needed to confirm clinical benefits of the therapy

Abstract

Although high-dose induction therapy is not a standard protocol, no clear adverse effects were observed, and treatment could be discontinued before 12 weeks in some cats. In cats in which treatment was shortened, improvement in SAA and α1AG concentrations appeared to be useful indicators for guiding treatment cessation. Further studies are required to clarify the clinical benefit of high-dose induction therapy.

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Discussion

Authors

Tsuyoshi Kamiyoshi

Noriko Kamiyoshi

C. Jintake

Journals

Journal of Feline Medicine and Surgery

Actions

Institutions

Kobe Asahi Hospital

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

EXPRESS: High-dose induction therapy and treatment termination criteria for feline infectious peritonitis with remdesivir and GS-441524

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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