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March 21, 2026Journal of Surgical Oncology0 citations

Impact of Aspirin on Recurrence Prevention After Curative Resection for Stage I–III Colorectal Cancer: A Multi‐Institutional Retrospective Study

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TBTomoaki BekkiMSManabu ShimomuraTYTakuya Yano

Key Result

Aspirin use is associated with improved postoperative prognosis in patients with stage I-III colorectal cancer after curative resection, particularly those with advanced-stage disease.

Key Points

  • This research aims to explore the effect of aspirin on recurrence rates after surgery in colorectal cancer patients.
  • Conducted a multi-institutional retrospective study
  • Included patients with stage I-III colorectal cancer
  • Analyzed postoperative outcomes in relation to aspirin use
  • Aspirin use is associated with improved postoperative prognosis
  • Particularly beneficial for advanced-stage patients
  • Supports the potential role of aspirin alongside adjuvant chemotherapy

Structured PICO

Does aspirin improve postoperative prognosis in patients with stage I-III colorectal cancer after curative resection?

P
Population
Patients with stage I-III colorectal cancer after curative resection
I
Intervention
Aspirin
O
Outcome
Recurrence prevention and postoperative prognosishard clinical

Aspirin use may improve postoperative prognosis and prevent recurrence in patients with stage I-III colorectal cancer following curative resection.

Abstract

This study suggests that aspirin use is associated with improved postoperative prognosis in patients with stage I-III colorectal cancer after curative resection. Aspirin may be beneficial for advanced-stage patients, for whom postoperative adjuvant chemotherapy is recommended.

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Cite This Study

Bekki et al. (2026) studied this question. Aspirin use is associated with improved postoperative prognosis in patients with stage I-III colorectal cancer after curative resection, particularly those with advanced-stage disease.

synapsesocial.com/papers/69be356f6e48c4981c673bebhttps://doi.org/10.1002/jso.70217
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