Reward learning mechanisms in anhedonia and dynamic modulation of perceived control

Key Points

• This research aims to explore the role of reward learning in anhedonia and how perceived control affects it.
• Conducted behavioral experiments and reinforcement learning modeling to assess perceived control.
• Utilized functional magnetic resonance imaging to investigate underlying neural mechanisms.
• Implemented a randomized controlled trial to intervene on perceived control and evaluate its impact on reward learning.
• Findings indicate that perceived control can dynamically modulate reward learning in individuals with anhedonia.
• The study proposes a dual-layer reward learning hypothesis to explain the mechanisms behind anhedonia.
• Interventions targeting perceived control show potential for improving reward learning and addressing anhedonia.