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March 22, 2026The International Journal of Gastroenterology and Hepatology Diseases

Relationship between Helicobacter pylori Infection and Metabolic Scores in Morbid Obese Subjects with Metabolically Dysfunctional Steatotic Liver Disease

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Authors

SHSeyed Ahmad HoseiniMSMohammadjavad Sotoudeheian

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Overview

Secondary analysis shows H. pylori infection fails to significantly impact metabolic scores in morbidly obese individuals.

Key Points

  • This research aims to explore the relationship between H. pylori infection and metabolic scores in morbidly obese individuals with liver disease.
  • Secondary analysis of 444 adults with morbid obesity
  • H. pylori status assessed through gastric biopsy
  • MASLD evaluated by liver biopsy in 93 patients
  • Metabolic indices calculated from fasting laboratory data
  • Statistical analyses included correlation analyses and RCS modeling.
  • 30% of participants had type-2 diabetes
  • 18% exhibited MASLD
  • No significant difference in metabolic scores between H. pylori-positive and -negative groups
  • Negligible correlation between infection status and metabolic scores
  • Higher TyG and TyG-BMI values modestly increased MASLD probability in H. pylori-positive patients.

Cite This Study

Hoseini et al. (2026) studied this question.

synapsesocial.com/papers/69bf390ac7b3c90b18b4321fhttps://doi.org/10.2174/0126662906458601260125221025
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