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March 22, 2026PLoS ONE0 citationsOpen Access

Thyroid Cancer Incidence Trends in China from 2005 to 2018: An Ecological Study

Spatial and temporal distribution of thyroid cancer incidence in China: An ecological study based on a national registry

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Authors

WLWen LiuJYJiaqi YangZZZhiwen Zheng

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Overview

Ecological study shows rising thyroid cancer incidence in urban areas versus rural, indicating a need for improved surveillance and prevention strategies.

Key Points

  • To analyze thyroid cancer incidence rates in China and understand its spatiotemporal distribution.
  • Analyzed national registry data from the China Cancer Registry (2005-2018)
  • Employed Joinpoint regression to assess time trends
  • Used age-period-cohort model for incidence analysis
  • Applied spatial autocorrelation to evaluate distribution patterns
  • Age-standardized incidence rate of thyroid cancer was 8.69 per 100,000
  • Observation of upward trend with an average annual percent change of 10.7%
  • Higher incidence in urban areas compared to rural
  • Incidence risk trend varies with age, showing initial increase then decline
  • Northeastern China displayed high-high clustering patterns
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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69bf390ac7b3c90b18b43427https://doi.org/10.1371/journal.pone.0341734
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