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March 22, 2026Hepatology Communications2 citationsOpen Access

B4GALT1 deficiency reduces steatohepatitis via PPARγ/ACSL4 axis regulation

B4GALT1 deficiency attenuates steatohepatitis by regulating the PPARγ/ACSL4 axis

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Authors

YCYoujung ChienRXRuiqi XiaDZDa Zhou

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Overview

B4GALT1 deficiency improves steatohepatitis by targeting lipid peroxidation in hepatocytes, suggesting it as a therapeutic target.

Key Points

  • This research explores how B4GALT1 deficiency affects steatohepatitis progression.
  • Investigated the role of B4GALT1 deficiency in steatohepatitis
  • Analyzed the PPARγ/ACSL4 axis
  • Examined lipid peroxidation in hepatocytes
  • B4GALT1 deficiency attenuates steatohepatitis
  • Regulates the PPARγ/ACSL4 axis
  • Targets lipid peroxidation in hepatocytes

Cite This Study

Chien et al. (2026) studied this question.

synapsesocial.com/papers/69bf3955c7b3c90b18b43ca6https://doi.org/10.1097/hc9.0000000000000920
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