There is a bidirectional relationship between epilepsy-related stigma (ERS) and medical outcomes.ERS negatively influences treatment adherence and disease management, whereas insufficient medical improvement can, in turn, exacerbate ERS.ERS remains a significant challenge, often leading to delays in diagnosis, limiting appropriate therapies, and creating difficulties in social integration for patients with epilepsy.Even when treatment successfully achieves seizure cessation, failure to address ERS can limit patient social integration, reduce quality of life, and hamper long-term psychosocial recovery.Previous studies suggest that a holistic and personalized medicine approach that addresses both the medical and psychosocial aspects of epilepsy, with a particular focus on reducing ERS, can significantly improve diagnosis and treatment outcomes.Integrating culturally sensitive mental health support and community-specific advocacy initiatives targeting ERS reduction into the routine management of epilepsy can promote clinical and psychosocial outcomes and help patients in their reintegration into normal daily life.Key initiatives may include personalized counseling to mitigate the emotional and psychological impact of ERS, targeted cultural competency training for healthcare professionals, and public awareness campaigns.Integrating these strategies into comprehensive epilepsy care is particularly important for marginalized populations, where poverty and limited healthcare access exacerbate ERS.A personalized anti-ERS plan that integrates individualized clinical management with targeted interventions designed for the specific ERS experiences of each patient can improve treatment adherence, enhance cognitive and emotional well-being, and promote better social integration by addressing both the psychological and social dimensions of ERS.
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Ghazaleh Ghorbannezhad
A. Gorji
Epilepsy & Behavior
University of Münster
Mashhad University of Medical Sciences
Khatam University
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Ghorbannezhad et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69bf8692f665edcd009e8ef5 — DOI: https://doi.org/10.1016/j.yebeh.2026.111002