A tailored transition program including bridging and post-discharge interventions will be evaluated for its efficacy in reducing 30-day unplanned rehospitalizations in high-risk multimorbid patients.
RCT
Stratified by cancer and heart failure
Open-label
No
Does a multimodal discharge intervention reduce the 30-day unplanned rehospitalization rate in high-risk adult internal medicine patients?
Adult patients hospitalized in an acute internal medicine department who are planned to be discharged home with a high estimated risk (≥20%, BARRS-Score ≥5) of 30-day rehospitalization.
Multimodal individualized discharge management by an interdisciplinary team (pre-discharge, bridging, and post-discharge interventions including 5-day daily phone follow-up).
Usual care (standard-of-care counselling before hospital discharge).
Rate of first unplanned rehospitalizations within 30 days after discharge from the index admission.hard clinical
Hospital rehospitalizations within 30 days represent a burden for patients and the healthcare system. Improving the care during the hospital discharge period could decrease the risk of avoidable rehospitalizations. To describe the methods of our trial aiming to define the efficacy of a tailored transition program in patients with high risk for rehospitalization compared to the usual discharge procedure with the endpoint of 30 day rehospitalization rate. Pragmatic, randomized, open-label, single-center superiority trial with a follow-up of 30 days. Included are adult patients hospitalized in an acute internal medicine department who are planned to be discharged home with a high estimated risk (20% or more) of 30-day rehospitalization. Patients in the intervention group will receive individualized and coordinated discharge management by an interdisciplinary team, compared to usual care in the control group. The multimodal intervention includes individualized pre-discharge, bridging, and post-discharge intervention components. Before enrolling the first patient, the trial was prospectively registered at the ISRCTN registry (registration date April 4th 2023) under the number ISRCTN11162162 and was approved by the ethical committee (Ethikkommission Nordwest- und Zentralschweiz (EKNZ), ID 2022–01040). This trial aims to assess the efficacy of a well-defined multicomponent discharge intervention to reduce unplanned rehospitalization rates in high-risk patients.
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Fabian Brennecke
Seraina Neurauter
Manuela Werner
Trials
University of Zurich
University of Bern
University Hospital of Bern
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Brennecke et al. (Fri,) conducted a rct in High risk for unplanned rehospitalization (n=1,704). Hospital@Home tailored transition program vs. Usual care was evaluated on Rate of first unplanned rehospitalizations within 30 days after discharge. A tailored transition program including bridging and post-discharge interventions will be evaluated for its efficacy in reducing 30-day unplanned rehospitalizations in high-risk multimorbid patients.
www.synapsesocial.com/papers/69bf86ecf665edcd009e9138 — DOI: https://doi.org/10.1186/s13063-026-09614-6
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