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March 26, 2026Molecular Genetics & Genomic Medicine0 citationsOpen Access

Clinical Utility of Prenatal cfDNA Screening for Sex Chromosome Aneuploidies: A Single Center Experience

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YLYing LinQLQun LuYWY. Wu

Key Points

  • This research aims to evaluate the effectiveness of prenatal cfDNA screening for detecting fetal sex chromosome aneuploidies.
  • Conducted at a single center
  • Utilized cfDNA screening for fetal genetic analysis
  • Compared cfDNA findings with routine ultrasound results
  • CfDNA screening effectively identified sex chromosome aneuploidies
  • Some cases detected by cfDNA would not have been spotted by ultrasound
  • Indicates cfDNA may improve prenatal detection rates

Abstract

Our findings demonstrated prenatal cfDNA screening as a unique approach to achieve effective detection of fetal SCAs, particularly those that otherwise would be overlooked by routine prenatal ultrasound screening.

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Cite This Study

Lin et al. (2026) studied this question.

synapsesocial.com/papers/69c4ccc9fdc3bde4489184f4https://doi.org/10.1002/mgg3.70211
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