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March 26, 2026European Eating Disorders Review0 citations

Heart Rate Variability in Anorexia Nervosa: A Systematic Review and Meta‐Analysis on the Moderating Role of Measurement Duration and Clinical Stage

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MSMarta Victoria SantiagoMHMiguel HeresCMCristina Mazas

Key Result

Heart rate variability in acute anorexia nervosa reflects parasympathetic predominance that does not consistently normalize during recovery, especially in short-term recordings.

Key Points

  • This research aims to evaluate how measurement duration and clinical stage affect heart rate variability in anorexia nervosa.
  • Conducted a systematic review and meta-analysis
  • Examined studies on heart rate variability in anorexia nervosa
  • Analyzed data based on measurement duration and clinical stages
  • Heart rate variability reflects autonomic changes in anorexia nervosa during the acute phase
  • Parasympathetic activity is predominant in this phase
  • Short-term recordings yield more consistent results regarding heart rate variability
  • Recovery does not consistently normalize heart rate variability

Structured PICO

Does heart rate variability reflect autonomic alterations across clinical stages in patients with anorexia nervosa?

P
Population
Patients with Anorexia Nervosa (AN)
I
Intervention
Heart Rate Variability (HRV) measurement
O
Outcome
Autonomic alterations (parasympathetic predominance) and normalization during recoverysurrogate

HRV assessment reveals persistent parasympathetic predominance in anorexia nervosa that does not reliably resolve with recovery, with short-term recordings yielding the most consistent data.

Abstract

Overall, HRV reflects autonomic alterations in AN, particularly in the acute phase characterised by parasympathetic predominance. HRV does not consistently normalise during recovery. These findings are strongly moderated by recording duration. Short-term recordings show more consistent effects.

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Cite This Study

Santiago et al. (2026) studied this question. Heart rate variability in acute anorexia nervosa reflects parasympathetic predominance that does not consistently normalize during recovery, especially in short-term recordings.

synapsesocial.com/papers/69c4ccc9fdc3bde4489185c5https://doi.org/10.1002/erv.70104
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