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Synapse
March 26, 2026European Journal of Neurology2 citationsOpen Access

Muscle MRI and Muscle Ultrasound Applications in MND / ALS : Academic Insights and Clinical Opportunities

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ATAlison ToomeyJKJana KleinerováETEe Ling Tan

Key Points

  • The aim is to explore the potential of muscle imaging techniques in understanding and managing MND/ALS.
  • Analysis of muscle imaging techniques including MRI and ultrasound.
  • Review of previous studies utilizing non-invasive imaging in similar neurological conditions.
  • Evaluation of the implementation of imaging protocols in clinical settings.
  • Identified significant potential for enhanced understanding of lower motor neuron dysfunction.
  • Highlighted the ease of integrating imaging techniques into clinical practice.
  • Showed promising outcomes in terms of patient independence and quality of life.

Abstract

Despite the huge impact of lower motor neuron dysfunction on the patients' independence, survival and quality of life, muscle imaging is a glaringly overlooked frontier of MND/ALS research. This is a missed opportunity, as a variety of non-invasive quantitative muscle imaging techniques have been successfully used in other neurological conditions; these protocols are easy to implement on commercial MRI and ultrasound platforms and recent studies have demonstrated their ease of use and potential clinical utility.

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Cite This Study

Toomey et al. (2026) studied this question.

synapsesocial.com/papers/69c4ccd6fdc3bde4489186c5https://doi.org/10.1111/ene.70582
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