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March 26, 2026Advances in Neonatal Care0 citations

Single Persistent Left Superior Vena Cava Draining Into the Left Atrium Causing Neonatal Cyanosis

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JRJudit Alsina RossellGGGisela Pérez GilFPFredy Prada

Key Points

  • To highlight the importance of considering a single persistent left superior vena cava (PLSVC) in neonates with unexplained cyanosis.
  • Review of cases with neonates presenting with hypoxemia and cyanosis.
  • Assessment of responses to standard treatments.
  • Cyanosis in neonates persisted despite standard treatments.
  • Detection of PLSVC provided insight into the underlying cause.

Abstract

In conclusion, although rare, a single PLSVC should be considered in the differential diagnosis of neonates with persisting hypoxemia and cyanosis that do not respond to standard treatments.

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Cite This Study

Rossell et al. (2026) studied this question.

synapsesocial.com/papers/69c4ccd6fdc3bde448918747https://doi.org/10.1097/anc.0000000000001346
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Persistent Left Superior Vena Cava. Surgical Implications, With Special Reference To Caval Drainage Into The Left Atrium1967 · 86 citations
  2. 2Left superior vena cava: revisited2012 · 106 citations
  3. 3Persistent Left Superior Vena Cava1972 · 240 citations
  4. 4Persistent left superior vena cava2017 · 87 citations
  5. 5Termination of Left Superior Vena Cava in Left Atrium, Atrial Septal Defect, and Absence of Coronary Sinus1965 · 313 citations