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March 26, 2026Acta Medica (Hradec Kralove Czech Republic)0 citationsOpen Access

Age-Related Variations in Enteric Glial Cells: A Comprehensive Microscopic Analysis of the Human Colon

AAAnwar AhmedSSSeema SinghAVAnand Verma

Key Points

  • The research aims to investigate how age affects the number and appearance of enteric glial cells in the human colon.
  • Conducted microscopic analysis of human colon samples across various age groups.
  • Quantified the number of enteric glial cells (EGCs).
  • Assessed morphological changes of EGCs with age.
  • Found a significant decrease in enteric glial cells with increasing age.
  • Documented notable morphological changes in EGCs as age progresses.
  • Proposed that these changes may relate to gut motility disorders in middle-aged individuals.

Abstract

There is a significant decrease in the number of EGCs with advancing age, along with notable morphological changes. These changes may contribute to various gut motility disorders observed in the middle-aged, impacting their quality of life.

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Cite This Study

Ahmed et al. (2025) studied this question.

synapsesocial.com/papers/69c4ccd6fdc3bde448918749https://doi.org/10.14712/18059694.2026.6
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