Chronic kidney disease (CKD) is a global healthcare issue that highlights the need for early identification for better quality of life for patients. This study evaluates various machine learning (ML) classifiers on datasets from UCI and self-collected sources in search of the best methods for CKD classification. This review examines commonly used ML models like support vector machine, K-nearest neighbor, naïve Bayes, decision trees, random forest, logistic regression and boosting-based ensemble methods. The results demonstrated the highest performance of ensemble methods. Despite these promising results, challenges related to model integration and interpretability still exist. Transparent models that are reliable and efficient are suitable for enhancement of clinical application(s). By overcoming these challenges, the work highlights importance of ML for CKD detection and treatment paving the way for artificial intelligence (AI)-driven healthcare solutions that are both effective and trustworthy.
Bhandurge et al. (2026) studied this question.