The study aims to achieve enantioselective electrophilic α-fluorination using an artificial metalloenzyme.
Utilized a Sav–biotin-based artificial metalloenzyme for catalysis.
Performed reactions to evaluate yields and enantioselectivities.
Achieved moderate to high yields in the fluorination reactions.
Demonstrated high enantioselectivity, indicating effective catalysis.
Abstract
Enantioselective electrophilic α-fluorination was achieved using a Sav–biotin-based artificial metalloenzyme with moderate to high yields and enantioselectivities.