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March 26, 2026Diagnostic Microbiology and Infectious DiseaseOpen Access

Is the Pneumococcal Urinary Antigen Test Still Fit for Purpose? A Decade of Experience

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Authors

SASaied Beshry AliKBKaren BurnsBDBinu Dinesh

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Overview

A retrospective review evaluates the clinical impact of pneumococcal urinary antigen testing, suggesting improved diagnostic stewardship.

Key Points

  • The study aims to evaluate the clinical impact and utilization of pneumococcal urinary antigen testing over ten years in a tertiary hospital.
  • Conducted a retrospective review of all PUA tests from 2014 to 2023.
  • Linked laboratory data with hospital discharge coding for CAP diagnoses.
  • Reviewed clinical records for positive tests to assess antimicrobial decision-making and vaccination recommendations.
  • 7,178 PUA tests performed with a positivity rate of 7.6%.
  • 42% of tests ordered lacked a CAP diagnosis, incurring avoidable costs of €17,000 annually.
  • 87% of positive results did not change antimicrobial therapy decisions.

Cite This Study

Ali et al. (2026) studied this question.

synapsesocial.com/papers/69c4cdb6fdc3bde44891a6abhttps://doi.org/10.1016/j.diagmicrobio.2026.117393
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