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March 27, 2026Kidney International Reports0 citationsOpen Access

Wcn26-6901 the Neutrophil to Lymphocite Ratio, and Platelat to Lymphocite Ratio as Prognostic Marker of Anca Associated Glomerulonephritis

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VRVioleta RabrenovićMRMilorad RabrenovićMPMilica Petrovic

Key Points

  • This research aims to evaluate the prognostic significance of NLR and PLR in ANCA-associated glomerulonephritis.
  • Analyzed the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR)
  • Assessed the association of these ratios with inflammatory activity
  • Studied the implications of NLR and PLR on renal disease progression
  • Higher NLR and PLR correlate with increased inflammatory activity
  • NLR and PLR are significant predictors of unfavorable disease outcomes
  • Potential use as biomarkers for assessing renal complications in ANCA vasculitis

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis is a serious manifestation of ANCA vasculitis (AAV), which occurs due to damage small blood vessels and glomeruli. The most serious complication occurs due to the progression of renal damage and the development of end-stage renal disease (ESRD). The aim of our study was to determine the derived markers NLR and PLR and indicate their significance in assessing inflammatory activity and predicting an unfavorable course.

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Cite This Study

Rabrenović et al. (2026) studied this question.

synapsesocial.com/papers/69c61fd715a0a509bde183echttps://doi.org/10.1016/j.ekir.2026.106283
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The neutrophil-to-lymphocyte ratio is associated with adverse outcomes in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis2026
  2. 2Diagnostic accuracy of <scp>ANCA</scp> serology in <scp>ANCA</scp>‐associated vasculitis with renal involvement2024 · 2 citations
  3. 3WCN24-391 Predictive Factors of Renal Recovery and Progression to End-Stage Kidney Disease in Patients with ANCA-Associated Vasculitis with Severe Kidney Disease2024
  4. 4Clinical investigation of patients with positive antineutrophil cytoplasmic antibodies (ANCA) test for autoimmunity and vasculitis2025
  5. 5Advances in the Diagnosis, Treatment and Prognosis of ANCA-Associated Glomerulonephritis2026