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March 27, 2026Kidney International Reports0 citationsOpen Access

WCN26-214 Association Between Ankle-Brachial Index and Coronary Artery Calcification Score in Patients Beginning Hemodialysis

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KYKiryu YoshidaHSHirohito SugawaraHMHiroki Mizuyama

Key Points

  • This research aims to explore the relationship between ankle-brachial index and coronary artery calcification score in patients starting hemodialysis.
  • Analyzed the association between ABI and CACS in patients starting hemodialysis.
  • Utilized non-invasive measures for ABI and computed tomography for CACS.
  • Focused on initial cardiovascular risk at the start of hemodialysis.
  • Identified distinct vascular calcification patterns related to ABI types.
  • Found low ABI correlates with intimal arterial calcification and high ABI with medial calcification.
  • Established that ABI may provide insights into coronary artery health at hemodialysis initiation.

Abstract

Patients initiating hemodialysis (HD) face a markedly increased risk of cardiovascular disease (CVD). The ankle-brachial index (ABI) is a simple, non-invasive marker reflecting distinct vascular calcification patterns: low ABI indicates intimal arterial calcification (IAC), while high ABI may reflect medial arterial calcification (MAC). Coronary artery calcium score (CACS), measured by computed tomography, represents coronary atherosclerosis but does not distinguish between IAC and MAC. Although several studies have examined ABI–CACS associations in maintenance dialysis, evidence at the time of HD initiation remains limited.

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Cite This Study

Yoshida et al. (2026) studied this question.

synapsesocial.com/papers/69c620d515a0a509bde196d5https://doi.org/10.1016/j.ekir.2026.104185
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