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March 27, 2026Kidney International Reports0 citationsOpen Access

WCN26-7803 Hemoadsorption (HA 230) in the Management of Severe Pit Viper Envenomation: A Case Report

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MMMaisie Mae Kathleen MarianoSRStephen Roberts

Key Points

  • To explore the effectiveness of hemoadsorption with HA 230 as an adjunctive treatment for severe pit viper envenomation.
  • Utilized hemoadsorption with HA 230 in a patient with severe envenomation symptoms
  • Monitored clinical outcomes and toxin levels pre- and post-treatment
  • Assessed improvements in acute kidney injury and coagulopathy
  • Significant reduction in circulating toxins after hemoadsorption
  • Improvement in kidney function and reduction of coagulopathy symptoms
  • Patient showed overall clinical recovery following treatment

Abstract

Snakebite envenomation continues to be a major health concern in tropical countries such as the Philippines, especially in rural areas where access to antivenom is limited. Pit viper envenomation can lead to local tissue necrosis, compartment syndrome, coagulopathy, and acute kidney injury (AKI). The lack of accessible antivenom in many hospitals exacerbates the challenge in managing these cases to which can lead to a potentially fatal outcome. Hemoadsorption with HA 230 offers a potential adjunctive treatment by removing circulating toxins and inflammatory mediators that contribute to organ dysfunction.

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Cite This Study

Mariano et al. (2026) studied this question.

synapsesocial.com/papers/69c620d515a0a509bde19794https://doi.org/10.1016/j.ekir.2026.106123
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