大黄䗪虫丸对胃癌并2型糖尿病患者化疗耐受性的影响

Key Points

• This research aims to evaluate the effect of Da Huang Chong Wan combined with XELOX chemotherapy on tolerance and quality of life in patients with gastric cancer and type 2 diabetes.
• 124 patients with gastric cancer and type 2 diabetes were randomly assigned to either control or observation groups.
• Both groups received XELOX chemotherapy, with the observation group receiving additional Da Huang Chong Wan.
• Rates of adverse reactions, chemotherapy withdrawal, and quality of life scores were monitored.
• Fasting blood glucose and postprandial blood glucose levels were also measured.
• The adverse reaction and chemotherapy withdrawal rates in the observation group were lower than those in the control group (P<0.05).
• Quality of life scores significantly improved in both groups post-treatment, with the observation group scoring higher than the control group (P<0.05).
• Fasting blood glucose and postprandial blood glucose levels were elevated in the control group after treatment, while they decreased in the observation group (P<0.05).

Abstract