What question did this study set out to answer?

To assess the impact of tranexamic acid on adipocyte differentiation and cell viability in vitro.

March 28, 2026

Investigating the Influence of Tranexamic Acid on Adipocyte Differentiation in an In Vitro Model

Puntos clave

To assess the impact of tranexamic acid on adipocyte differentiation and cell viability in vitro.
Evaluated effects of clinically relevant concentrations of tranexamic acid on adipose progenitor cells.
Analyzed cell viability and proliferation of progenitor cells after treatment with tranexamic acid.
Assessed adipogenic differentiation and thermogenic responsiveness of adipose progenitor cells.
Tranexamic acid did not impair cell viability or proliferation of adipose progenitor cells.
No adverse effects on adipogenic differentiation were observed in treated cells.
Thermogenic responsiveness was maintained in the presence of tranexamic acid.

Resumen

Clinically relevant concentrations of TXA do not impair adipose progenitor cell viability, proliferation, adipogenic differentiation, or thermogenic responsiveness in vitro. These findings support the cellular safety of TXA use in liposuction and fat grafting and provide reassurance as adoption of TXA continues to expand in plastic and reconstructive surgery.

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Cite This Study

Ellis et al. (Thu,) studied this question.

synapsesocial.com/papers/69c772718bbfbc51511e2f82 https://doi.org/https://doi.org/10.1097/sap.0000000000004702

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