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March 29, 2026SHILAP Revista de lepidopterología0 citationsOpen Access

Biomolecular Phase Separation and Colloidal Theory: Health and Disease Implications

From the classical colloidal theory to biomolecular condensation: implications in health and disease

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Authors

NMNoelia A. MelianAGAldana GomezMAMilagros B. Abate

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Overview

This article integrates classical colloidal theory with biomolecular condensation to explore health implications and disease mechanisms.

Key Points

  • The research aims to connect classical colloidal theory with biomolecular condensation and its implications in health and disease.
  • Integrated classical colloidal theory with biomolecular phase separation concepts.
  • Examined the effects of pH, ionic strength, metal ions, and post-translational modifications.
  • Analyzed how these factors influence assembly dynamics and properties of biomolecular condensates.
  • Identified key physicochemical parameters that modulate biomolecular condensation.
  • Established a link between phase separation, health mechanisms, and disease processes.
  • Highlighted the catalytic activity of amyloid-promoting proteins in condensed states.

Cite This Study

Melian et al. (2026) studied this question.

synapsesocial.com/papers/69c8c115de0f0f753b39b9f9https://doi.org/10.3389/frbis.2026.1795884
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