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March 29, 2026American Journal of Neuroradiology0 citationsOpen Access

Systematic Review and Meta-Analysis on Rescue Stenting for Large-Vessel Occlusion due to Underlying Intracranial Atherosclerotic Stenosis (ICAS)

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FMFrancesco MarinoGPGuglielmo PeroSBS Borzi

Key Points

  • This research aims to evaluate the effectiveness of rescue stenting for large-vessel occlusion due to intracranial atherosclerotic stenosis.
  • Conducted a systematic review and meta-analysis
  • Analyzed reperfusion rates and functional outcomes
  • Assessed rates of symptomatic haemorrhage and mortality benefits
  • Rescue stenting showed higher reperfusion rates in patients
  • Improved functional outcomes at 90 days observed
  • No statistically significant increase in symptomatic haemorrhage noted
  • Uncertainty remains regarding the mortality benefit

Abstract

In large-vessel occlusion due to intracranial atherosclerotic stenosis, rescue stenting is associated with higher reperfusion rates and improved 90-day functional outcomes without a statistically significant increase in symptomatic haemorrhage, while any mortality benefit remains uncertain. The certainty of the evidence is low, and randomized data are needed to confirm causality and optimize patient selection.

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Cite This Study

Marino et al. (2026) studied this question.

synapsesocial.com/papers/69c8c195de0f0f753b39bf08https://doi.org/10.3174/ajnr.a9318
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