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March 29, 2026Clinical Infectious Diseases1 citationsOpen Access

Age-Specific Risk of Herpes Zoster in Adults Aged ≥18 Years With Comorbid Conditions—A Retrospective Cohort Study in the United States

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RCRachel A CohenDODriss OraichiAMAgnes Mwakingwe-Omari

Key Points

  • To assess the risk of herpes zoster in adults with specific comorbid conditions across different age groups.
  • Retrospective cohort study design
  • Analysis of medical records of adults aged 18+
  • Comparison of herpes zoster risk in younger adults versus immunocompetent adults aged 50-59
  • Younger adults (30+ years) with comorbidities show higher risk of herpes zoster than immunocompetent adults aged 50-59
  • Specific comorbid conditions significantly influence herpes zoster risk

Abstract

The study found that younger adults (30+ YoA) with certain comorbidities have a higher HZ risk than immunocompetent 50-59 YoA adults.

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Cite This Study

Cohen et al. (2026) studied this question.

synapsesocial.com/papers/69c8c30dde0f0f753b39d930https://doi.org/10.1093/cid/ciag095
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Age-specific risk of herpes zoster in immunocompetent adults ≥18 years-of-age – a retrospective cohort study in the United States2026
  2. 2Risk of herpes zoster among adults in the United States initiating immunosuppressive therapy: A retrospective cohort study2026
  3. 3Preventing herpes zoster in immunocompromised patients: Current concepts2024 · 10 citations
  4. 4Rising Burden of Herpes Zoster among General Adults and Increased-Risk Groups in Eastern China, 2015–2021: A Population-Based Cohort Study2026 · 1 citations
  5. 5Burden of herpes zoster in adults by age, sex, and underlying conditions in Taiwan: A retrospective cohort study, 2011–20202025