Abstract Allogenic hematopoietic stem cell transplant is becoming a standard treatment for hematologic malignancies, with haploidentical transplants gaining interest. Chronic Graft-versus-host-disease (GVHD) often presents cutaneous symptoms. This case study describes a pediatric patient with Down’s syndrome who developed rare soft-tissue calcinosis linked to chronic GVHD.
Negrete-Rodríguez et al. (2026) studied this question.