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March 29, 2026BMC GenomicsOpen Access

Genetic analysis of cold tolerance and high-altitude adaptation in Gannan indigenous Tibetan sheep through genome-wide scans

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Authors

CLChenxiao LvLCLili ChenPZPan Zou

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Overview

Genome-wide scans identify genes linked to cold tolerance and adaptation in Gannan Tibetan sheep, suggesting evolutionary advantages.

Key Points

  • This study aims to understand the genetic adaptations that allow Gannan Tibetan sheep to thrive in high-altitude and cold environments.
  • Conducted whole-genome resequencing of three indigenous Tibetan sheep breeds.
  • Integrated genomic data with previously published information from other northern Chinese sheep breeds.
  • Analyzed genetic population structure, ancestry components, and positive selection signatures.
  • Identified genes associated with cold tolerance and high-altitude adaptation.
  • Revealed high genetic diversity among the three breeds, enhancing their adaptive capabilities.
  • Discovered candidate regions for immunity and physical traits related to environmental adaptation.

Cite This Study

Lv et al. (2026) studied this question.

synapsesocial.com/papers/69c8c35cde0f0f753b39e0f2https://doi.org/10.1186/s12864-026-12722-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analysis of Migration and Adaptive Evolution in Tibetan Sheep Populations2026
  2. 2Genome-wide selection signal analysis reveals the adaptability of Tibetan sheep to high altitudes.2025
  3. 3Multi-omic Analyses Shed Light on The Genetic Control of High-altitude Adaptation in Sheep2024 · 11 citations
  4. 4Population Structure and Genetic Diversity of Tibetan Sheep Revealed by Whole-Genome Resequencing: Implications for Conservation and Breeding2025 · 2 citations
  5. 5Whole-genome resequencing of Chinese indigenous sheep provides insight into the genetic basis underlying climate adaptation2024 · 17 citations