We disclose a neuromodulation system implementing closed-loop, magnetically-mediated temporal interference stimulation (m-tTIS). While inspired by traditional electric tTIS, the disclosed architecture utilizes coherent magnetic field synthesis for non-invasive tissue penetration. To suppress electromagnetic interference (EMI) below functional detection thresholds and limit hardware-induced demodulation artifacts, an "Absolute Optical Air-Gap" architecture is detailed. The device is partitioned into galvanically isolated domains, interconnected exclusively via plastic optical fiber (POF). The power stage employs a Class D amplifier with a second-order LC filter and hardware current sensing for amplitude stabilization. Control is based on adaptive optimization of physiological spectral metrics. Firmware execution provides deterministic, bounded latency enforced by hardware timing primitives. This disclosure establishes prior art across biomedical and industrial coherent field control applications.
Olexandr Lozovyi (2026) studied this question.