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March 30, 2026Journal of Investigative Medicine High Impact Case Reports0 citationsOpen Access

Suspected Cannabis-Induced Acute Coronary Syndrome and Advanced Heart block

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AMArun MaharajPNPravin NangaAKArun Katwaroo

Key Points

  • To detail the case of a patient with acute coronary syndrome associated with cannabis consumption and advanced heart block.
  • Case report of a 35-year-old Caribbean-Black male with a cannabis history.
  • Patient presented with ST-segment-elevation acute coronary syndrome and underwent percutaneous coronary intervention.
  • Cineangiography and aspiration thrombectomy were performed as part of treatment.
  • Significant thrombus burden was found in the right coronary artery.
  • The patient underwent successful aspiration thrombectomy and angioplasty with a drug-coated balloon.
  • Guideline-directed medical therapy including oral anticoagulation was initiated.

Abstract

We describe a 35-year-old Caribbean-Black male patient with a significant cannabis history who presented with an inferior ST-segment-elevation acute coronary syndrome (STE-ACS), with advanced heart block during active, ongoing cannabis consumption. During primary percutaneous coronary intervention, cineangiography revealed substantial thrombus burden in the first acute marginal branch of the right coronary artery. He successfully underwent aspiration thrombectomy with subsequent angioplasty with a drug-coated balloon and guideline-directed medical therapy, including direct oral anticoagulation. The clinician should be cognizant of the association between ACS and both acute and chronic cannabis consumption.

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Cite This Study

Maharaj et al. (2026) studied this question.

synapsesocial.com/papers/69c9c5c5f8fdd13afe0bdd59https://doi.org/10.1177/23247096261435473
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cannabis-induced myocardial infarction in a 27-year-old man: Case report2022 · 6 citations
  2. 2Cannabis-Induced ST-Segment Elevation Myocardial Infarction With Possible Coronary Artery Dissection: A Case Report2023 · 1 citations
  3. 3Spontaneous Coronary Artery Dissection in the Setting of Marijuana: A Case Report2024
  4. 4Marijuana-induced Coronary Vasospasm with Persistent Inter-coronary Connection: A Case Report and Review of Literature2019 · 7 citations
  5. 5Acute myocardial infarction with multiple coronary thrombosis in a young multidrug addict (amphetamines, cannabinoids, and tramadol): a case report2021