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March 31, 2026EBioMedicine0 citationsOpen Access

Elevated body mass index is associated with delayed protective airway mucosal immune responses in mild SARS-CoV-2 infection

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JFJoe FennRKRhia KunduJNJanakan Sam Narean

Key Points

  • The study aims to explore the relationship between elevated body mass index and immune response timing during mild SARS-CoV-2 infection.
  • Analyzed body mass index in relation to immune responses.
  • Conducted assessments on mild SARS-CoV-2 infection cases.
  • Employed statistical analyses to determine associations.
  • Elevated body mass index correlates with delayed airway mucosal immune responses.
  • This delay may affect overall infection outcomes.
  • Findings suggest potential targets for improving treatment in obese individuals.

Abstract

This work is supported by the NIHR Health Protection Research Unit in Respiratory Infections, Imperial College London in partnership with the UK Health Security Agency (Grant number: NIHR200927; AL) and the Medical Research Council (Grant number: MR/X004058/1). Infrastructure support for this research was provided by the NIHR Imperial Biomedical Research Centre (BRC).

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Cite This Study

Fenn et al. (2026) studied this question.

synapsesocial.com/papers/69cb63c9e6a8c024954b883fhttps://doi.org/10.1016/j.ebiom.2026.106215
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