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April 1, 2026Journal of Biorheology0 citationsOpen Access

Thickness effects in particle-tracking microrheology measurements of a fluid in a thin channel between gel and glass

AEAmane EndoYMYasuyuki MakiMAMasahiko Annaka

Key Points

  • The aim is to explore how the thickness of a fluid layer impacts particle mobility during microrheology measurements.
  • Applied particle-tracking microrheology to a water layer between gel and glass surfaces.
  • Measured the diffusion coefficient of particles at varying thickness and particle sizes.
  • Compared findings with predictions from the Faxén equation.
  • Diffusion coefficient decreased as the thickness to particle radius ratio decreased.
  • Results closely aligned with theoretical predictions from the Faxén equation.

Abstract

Particle-tracking microrheology was applied to a water layer less than a hundred micrometer thick sandwiched between gel and glass surfaces. The diffusion coefficient of the particles tended to decrease as the ratio of thickness to the particle radius decreased. The experimental results were in good agreement with the Faxén equation for particle mobility, which is derived by considering the hydrodynamic interaction between the particle and two solid surfaces.

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Cite This Study

Endo et al. (2025) studied this question.

synapsesocial.com/papers/69ccb55116edfba7beb874e2https://doi.org/10.17106/jbr.39.102
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