A Microneedle with Photoactive Electrospun Backing Layer Enables Multitherapy and Combined Drug Delivery to the Skin Wound

Key Points

• To explore a microneedle system with a photoactive backing for effective drug delivery to skin wounds.
• Developed a microneedle with a photoactive electrospun layer.
• Assessed the ability for multitherapy in wound healing.
• Analyzed effectiveness of drug delivery in various skin wound models.
• Improved healing observed in test subjects using the microneedle system.
• Increased drug absorption and reduced infection rates noted.
• Demonstrated potential for simultaneous treatment of multiple wound barriers.

Abstract