Mechanically Induced Dentin Mineralization and DMP1 Upregulation Following Orthodontic Tooth Movement

Key Points

• This research aims to explore how orthodontic tooth movement affects dentin mineralization and related molecular changes.
• Used a rat model for the study
• Applied continuous mechanical forces to simulate orthodontic tooth movement
• Analyzed dentin mineralization and molecular responses, particularly DMP1 levels
• Dentin mineralization increased following application of mechanical forces
• DMP1 expression levels were significantly upregulated in response to orthodontic treatment