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April 1, 2026内科诊疗与进展0 citationsOpen Access

阿仑膦酸钠对绝经后骨质疏松患者腰椎骨密度的改善作用研究

李李海英

Key Points

  • This research aims to explore the effects of alendronate on lumbar bone density in postmenopausal osteoporosis patients and its clinical application value.
  • 120 postmenopausal osteoporosis patients were divided into observation and control groups.
  • Control group received standard treatment, while the observation group received alendronate in addition.
  • Treatment duration was 12 months.
  • Changes in lumbar bone density, bone turnover markers, and pain scores were compared pre- and post-treatment.
  • After 12 months, the observation group showed a significant increase in lumbar bone density.
  • Bone turnover markers improved markedly in the observation group.
  • Bone pain symptoms were significantly relieved compared to the control group.

Abstract

目的:探讨阿仑膦酸钠对绝经后骨质疏松患者腰椎骨密度的改善效果及临床应用价值。方法:选取2022 年1月至2024年1月在我院就诊的绝经后骨质疏松患者120例,采用随机数字表法分为观察组和对照组各60例。对照组 给予基础治疗,观察组在对照组基础上加用阿仑膦酸钠治疗,治疗周期为12个月。比较两组患者治疗前后的腰椎骨密 度(l2-L4)、骨转换标志物及骨痛评分变化情况。结果:治疗12个月后,观察组患者的腰椎骨密度显著提高,骨转 换标志物水平明显改善,骨痛症状明显缓解,与对照组比较差异具有统计学意义(p < 0.05)。结论:阿仑膦酸钠能 够有效改善绝经后骨质疏松患者的腰椎骨密度,调节骨代谢,缓解骨痛症状,具有良好的临床应用价值。

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Cite This Study

李海英 (2025) studied this question.

synapsesocial.com/papers/69cd79e15652765b073a6c60https://doi.org/10.37155/2717-5693-0604-35
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