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April 1, 2026Clinical and Experimental Obstetrics & GynecologyOpen Access

From Immune Dysregulation to Precision Immunotherapy in Recurrent Pregnancy Loss: A Narrative Review

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Authors

LPLin PeiTWTing WangPYPengchao Yan

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Overview

Narrative review explores immune causes of recurrent pregnancy loss, suggesting precision therapies could improve treatment outcomes.

Key Points

  • This review examines immune-related mechanisms underlying recurrent pregnancy loss and potential precision treatments.
  • Reviewed literature on immune dysregulation and its impact on recurrent pregnancy loss.
  • Analyzed new technologies like single-cell RNA sequencing and proteomic profiling for immune cell profiling.
  • Discussed emerging therapeutic options such as immunomodulation and biologic agents.
  • Identified specific immune mechanisms contributing to recurrent pregnancy loss.
  • Highlighted candidate biomarkers that differentiate immune tolerance from inflammation.
  • Proposed advancements toward personalized immunotherapy based on immune profiling and multi-omics technologies.

Cite This Study

Pei et al. (2026) studied this question.

synapsesocial.com/papers/69cd7a815652765b073a7b04https://doi.org/10.31083/ceog48244
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