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April 1, 2026Journal of the American Heart Association0 citationsOpen Access

Implementing the GWTG‐CAD Program in Mexico: Feasibility, Challenges and Lessons Learned for Acute and Secondary Prevention and Management

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LLLeslie Marisol Lugo‐GavidiaJSJorge F. SaucedoAAAlexandra Arias‐Mendoza

Key Result

Implementation of the GWTG-CAD program in Mexico increased the proportion of patients receiving an ECG within 10 minutes of arrival from 61% to 93% over 18 months.

Key Points

  • This study aims to evaluate the implementation of the GWTG‐CAD program in Mexico and its impact on adherence to medical guidelines and clinical processes.
  • Analyzed patients with acute coronary syndrome from 10 hospitals in Mexico.
  • Utilized the GWTG‐CAD registry to collect data on clinical processes and guideline adherence.
  • Performed assessments over 18 months, divided into preprogram and subsequent intervals.
  • Significant increase in ECG administration within 10 minutes from 61% to 93% (P < 0.001).
  • Reduction in mean time to first ECG from 23.3 to 8.5 minutes (P < 0.001).
  • Consistent adherence to guideline-directed medical therapy at discharge remained above 85%.
  • Notable improvements in ECG documentation (89% to 97.3%) and symptom onset recording (79.7% to 90.1%).
  • Increased left ventricular ejection fraction assessment from 73.4% to 87.5% and lipid profile measurement from 42.7% to 72% (all P < 0.001).

Structured PICO

Does the implementation of the GWTG-CAD program improve adherence to guideline-directed medical therapy and clinical processes in patients with acute coronary syndrome?

P
Population
Patients presenting with acute coronary syndrome (mean age 62.7, 73.4% male, 65.4% STEMI)
I
Intervention
Implementation of the GWTG-CAD (Get With The Guidelines - Coronary Artery Disease) program
C
Comparator
Preprogram period (historical control)
O
Outcome
Adherence to guideline-directed medical therapy and key clinical processes (e.g., time to first ECG)surrogate

Implementation of the GWTG-CAD quality improvement program in Mexico significantly improved time-sensitive acute coronary syndrome care and adherence to clinical process guidelines over 18 months.

Abstract

Background The American Heart Association's GWTG (Get With The Guidelines) program has demonstrated effectiveness in standardizing and improving cardiovascular care in the United States. This study describes the implementation of the GWTG‐CAD (GWTG–Coronary Artery Disease) program in Mexico and evaluates its impact on adherence to guideline‐directed medical therapy and key clinical processes. Methods Patients presenting with acute coronary syndrome from 10 hospitals in Mexico were included in the GWTG‐CAD registry. Clinical processes and guideline‐directed medical therapy use were assessed over the program's first 18 months, grouped into preprogram, 0 to 6 months, 6 to 12 months, and 12 to 18 months. Results A total of 2363 patients were analyzed. Mean age was 62.7±12.4 years, and 73.4% were male. ST‐segment–elevation myocardial infarction was the initial presentation in 65.4% (n=1546). Substantial improvements were achieved in time‐sensitive care. The proportion of patients receiving an ECG within 10 minutes of arrival increased from 61% preprogram to 93% at 12to 18 months ( P 85%. Significant improvements were observed on health processes, including ECG documentation (89%–97.3%), symptom onset recording (79.7%–90.1%), left ventricular ejection fraction assessment (73.4%–87.5%), and lipid profile measurement (42.7%–72%) (all P <0.001). Conclusions Implementation of the GWTG‐CAD program in Mexico enabled the identification of critical barriers in cardiac care and supported targeted quality‐improvement strategies, resulting in measurable improvements in clinical processes over 18 months.

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Cite This Study

Lugo‐Gavidia et al. (2026) studied this question. Implementation of the GWTG-CAD program in Mexico increased the proportion of patients receiving an ECG within 10 minutes of arrival from 61% to 93% over 18 months.

synapsesocial.com/papers/69cd7b695652765b073a9699https://doi.org/10.1161/jaha.125.045698
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