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April 3, 2026Revista da Associação Médica Brasileira0 citationsOpen Access

Preclinical safety and efficacy of “Yubivaks,” a natural ointment for burn wounds: acute dermal toxicity and irritancy evaluation

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SPSusanna Babken PoghosyanKAKaren Avetik AkopianSTSiranush Hovannes Ter-Zaqaryan

Key Points

  • This research aims to evaluate the safety and efficacy of Yubivaks ointment for treating burn wounds.
  • Conducted toxicity and irritancy tests on rats and rabbits.
  • Administered the ointment at recommended therapeutic doses.
  • Measured regenerative and anti-inflammatory effects.
  • Yubivaks ointment accelerated regenerative processes in burn wounds.
  • Demonstrated significant anti-inflammatory properties.
  • Proven safety in experimental animal models.

Abstract

At the recommended therapeutic dose, the ointment can be considered as an alternative medication due to accelerated regenerative processes, pronounced anti-inflammatory properties, and safety proven in experimental studies. A limitation of the study was that it was only conducted on rats and rabbits, without using guinea pigs or pig models for several reasons.

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Cite This Study

Poghosyan et al. (2026) studied this question.

synapsesocial.com/papers/69cf588f5a333a82146097dbhttps://doi.org/10.1590/1806-9282.20250666
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