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April 3, 2026JAMA Dermatology0 citations

Risk of Skin Cancer Among Patients With Chronic Lymphocytic Leukemia

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ADAstrid Merete Blomberg DrejøeMHMathilde N. HemmingsenIWIda Karoline Wulff

Key Points

  • This study aims to evaluate the risk of skin cancer among patients with chronic lymphocytic leukemia (CLL).
  • Cohort study design
  • Analysis of skin cancer incidence among CLL patients
  • Comparison of cancer-related outcomes with all-cause mortality
  • CLL patients had a higher risk of developing skin cancer, particularly basal cell and squamous cell carcinoma.
  • Skin cancer metastasis and mortality were more common in CLL patients, though overall mortality was significantly higher.

Abstract

This cohort study found that patients with CLL had an increased risk of developing skin cancer, mainly basal cell carcinoma and squamous cell carcinoma. Skin cancer-specific metastasis and death were also more frequent among patients with CLL, although the absolute risk remained low given markedly higher all-cause mortality.

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Cite This Study

Drejøe et al. (2026) studied this question.

synapsesocial.com/papers/69cf5ced5a333a821460a845https://doi.org/10.1001/jamadermatol.2026.0355
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