Abstract Objective To evaluate reviews focused on adult outcomes of patients with complex neonatal history. Study design We searched multiple databases in January 2022 and supplemented by hand searching references in included reviews. Two authors assessed reviews for eligibility. Data were extracted by one author, verified by a second. Counts based on neonatal exposure, adult outcome, and journal type for each review were calculated. Results Eight-seven reviews were included. Most focused on prematurity. The most common adult outcome assessed was cardiovascular. Papers shifted to publication in pediatric journals over the last decade. Gaps include a lack of reviews focused on those with a history of substance exposure in utero and a lack of reviews on adult autoimmune conditions and gynecologic outcomes. Conclusion Reviews of adult outcomes of those with complex neonatal history have moved to publication in pediatric journals recently. We identified gaps in both pediatric populations and adult outcomes assessed.
Hart et al. (2026) studied this question.