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April 3, 2026Journal of Hepato-Biliary-Pancreatic Sciences0 citations

Tumor Cell Count and Total Cell Count as Surrogate Indicators of Comprehensive Genomic Profiling Success in Pancreatic Cancer Specimens Collected by Endoscopic Ultrasonography‐Guided Tissue Acquisition

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GIG. IkedaSHSusumu HijiokaYTYuka Takahashi

Key Points

  • The aim is to evaluate tumor and total cell counts as indicators for genomic profiling success in pancreatic cancer specimens.
  • Evaluated tumor and total cell counts in pancreatic cancer specimens collected by endoscopic ultrasonography guided tissue acquisition.
  • Identified specific thresholds for tumor cell count (≥ 2300) and total cell count (≥ 6000) to assess specimen suitability.
  • Analyzed the relevance of tumor cell count in relation to comprehensive genomic profiling.
  • Tumor cell count of ≥ 2300 effectively indicates specimen suitability for genomic profiling.
  • Total cell count of ≥ 6000 serves as a supplementary indicator for assessing specimen quality.

Abstract

Tumor cell counts ≥ 2300 and total cell counts ≥ 6000 may serve as surrogate criteria for tissue area to determine EUS-TA specimen suitability for CGP in pancreatic cancer. Given that tumor cell count is a more biologically relevant indicator, total cell count should be used as a supplementary indicator.

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Cite This Study

Ikeda et al. (2026) studied this question.

synapsesocial.com/papers/69cf5dc55a333a821460bb8ehttps://doi.org/10.1002/jhbp.70106
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