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April 3, 2026Cornea1 citations

The “Polish Sign”: A Novel Intraoperative Visual Indicator During Descemet Membrane Polishing in Cultured Human Corneal Endothelial Cell Injection Therapy

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AKAkira KobayashiTYTakefumi YamaguchiSSSeiichiro Sugita

Key Points

  • This research aims to evaluate the effectiveness of the Polish Sign as an indicator during Descemet membrane polishing.
  • Introduced the Polish Sign as a real-time visual indicator during the surgical procedure.
  • Assessed the visibility of the sign in the presence of stromal opacity and adjusted illumination for better recognition.
  • The Polish Sign effectively minimizes the risk of Descemet membrane injury.
  • Visibility may decrease in eyes with dense stromal opacity, but enhanced illumination can improve recognition.

Abstract

The polish sign provides a simple, real-time indicator that enables safe and consistent DM polishing while minimizing the risk of DM injury. Although its visibility may decrease in eyes with dense stromal opacity, adjusting illumination can enhance recognition, suggesting that the sign may have relevance across various endothelial cell-based therapies.

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Cite This Study

Kobayashi et al. (2026) studied this question.

synapsesocial.com/papers/69cf5dc55a333a821460bc6chttps://doi.org/10.1097/ico.0000000000004092
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