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April 3, 2026JAMA Network Open0 citationsOpen Access

COVID-19 Vaccine Framing and Acceptance Among Adults Who Are Vaccine Hesitant

PKParthasarathy KrishnamurthyYHYe Hu

Key Points

  • This research aims to explore how different types of messaging influence vaccine acceptance among adults who are hesitant about vaccination.
  • Cross-sectional design to assess framing effects on vaccine acceptance.
  • Comparison of government recommendation framing, freedom framing, and protect-others framing.
  • Target population included adults categorized as vaccine hesitant.
  • Freedom framing was linked to higher vaccine acceptance among vaccine hesitant adults.
  • Protect-others framing positively affected vaccine acceptance regardless of hesitancy levels.
  • Overall increases in vaccine acceptance were considered modest.

Abstract

This cross-sectional study found that compared with government recommendation framing, freedom framing was selectively associated with higher vaccine acceptance among adults who were vaccine hesitant. Protect-others framing was associated with higher vaccine acceptance regardless of hesitancy level. Absolute gains in acceptance were modest. These findings highlight how autonomy-consistent framing may influence stated vaccine preferences among hesitant adults.

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Cite This Study

Krishnamurthy et al. (2026) studied this question.

synapsesocial.com/papers/69cf5de95a333a821460bf12https://doi.org/10.1001/jamanetworkopen.2026.4114
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