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April 3, 2026Journal of the American Medical Informatics Association

A systematic methodological review of best practices, pitfalls, and opportunities in mixed methods research in applied clinical informatics

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Authors

ONOliver T. NguyenAAArsalan AhmadMDMichelle Doering

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Overview

This systematic review identifies reporting issues in mixed methods studies of clinical informatics, suggesting improved guidelines are needed.

Key Points

  • The review aims to evaluate the application of mixed methods in clinical informatics intervention studies and identify common pitfalls.
  • Conducted a systematic search in multiple databases for studies using mixed methods.
  • Characterized themes and designs of informatics intervention studies.
  • Assessed study quality using the Mixed Methods Appraisal Tool.
  • Included 54 studies in the review.
  • 25.9% of studies misclassified as mixed methods did not integrate data types.
  • Common use during pre- and post-implementation evaluations was noted.

Cite This Study

Nguyen et al. (2026) studied this question.

synapsesocial.com/papers/69cf5e2e5a333a821460c602https://doi.org/10.1093/jamia/ocag035
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