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April 3, 2026Annals of Clinical and Translational Neurology0 citationsOpen Access

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

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GHGuangsong HanJPJiachun PanYHYuehui Hong

Key Points

  • This study investigates how different forms of moyamoya vasculopathy relate to cerebral infarction using high-resolution MRI.
  • Used high-resolution MRI to derive quantitative vascular metrics.
  • Analyzed ischemia-related patterns in moyamoya disease and atherosclerosis-associated moyamoya vasculopathy.
  • Compared middle cerebral artery and anterior cerebral artery remodeling in different etiology groups.
  • Identified global steno-occlusive burden and impaired middle cerebral artery remodeling in moyamoya disease.
  • Detected adverse middle cerebral artery remodeling and anterior cerebral artery involvement in atherosclerosis-associated vasculopathy.
  • Established distinct ischemic patterns related to the underlying pathology.

Abstract

High-resolution MRI-derived quantitative vascular metrics show distinct ischemia-related patterns in moyamoya disease and atherosclerosis-associated moyamoya vasculopathy. Global steno-occlusive burden with impaired middle cerebral artery remodeling characterizes ischemic hemispheres in moyamoya disease, whereas adverse middle cerebral artery remodeling and anterior cerebral artery involvement are key correlates of ischemia in atherosclerosis-associated moyamoya vasculopathy.

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Cite This Study

Han et al. (2026) studied this question.

synapsesocial.com/papers/69cf5e5f5a333a821460ca44https://doi.org/10.1002/acn3.70380
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