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April 3, 2026Asian journal of pediatric dermatology.0 citations

An Infant with Pigmented Lesions and a Positive Darier’s Sign

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SASarita AsotraSDShailez Daroch

Key Points

  • This case report aims to describe the diagnosis and treatment of urticaria pigmentosa in an infant.
  • Clinical observation of pigmented lesions
  • Histopathologic examination via skin biopsy
  • Assessment of treatment with antihistamines and topical corticosteroids
  • Diagnosis confirmed based on clinical signs and biopsy results
  • Multiple brownish patches appeared at 2 months of age
  • Lesions identified on scalp, trunk, and limbs
  • Condition is generally benign and self-resolving

Abstract

Abstract Urticaria pigmentosa is the most common form of cutaneous mastocytosis, in children and can be present in adult as well. It is generally considered a benign, self-resolving condition that often remits in adolescence. It can be diagnosed clinically, based on the appearance of numerous small yellow- brown macules and papules that urticate when rubbed and are symmetrically distributed , mostly on the trunk and the extremities. Skin biopsy is helpful in establishing the diagnosis. Treatment options generally include antihistamines and/ or topical corticosteroids. In this case report , we present the case of a of a 5 month old male child with history of multiple brownish patches over scalp, trunk, bilateral upper and lower limb which started when he was 2 months old. He was diagnosed with Urticaria pigmentosa based on clinical and histopathologic findings.

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Cite This Study

Asotra et al. (2025) studied this question.

synapsesocial.com/papers/69cf5e745a333a821460cd22https://doi.org/10.4103/ajpd.ajpd_12_25
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