Interactions of IOX1, a histone demethylase inhibitor, with essential metal ions, albumin, and its clay-based nanoformulation

Key Points

• This research investigates the chemical behavior and interactions of IOX1 in solution, particularly with essential metal ions and albumin.
• Characterization of IOX1 in aqueous solution
• Analysis of complex formation with metal ions
• Evaluation of interactions with albumin
• Assessment of nanoformulation properties
• IOX1 shows strong interactions with specific metal ions
• Complex formation equilibria were established
• The clay-based nanoformulation enhances the stability of IOX1
• Interactions with albumin were characterized, suggesting potential for drug delivery.