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April 4, 2026Neurological Research1 citations

Serum endocan as a circulating biomarker following experimental spinal cord injury in rats

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HKHümeyra KullukçuKÇKadir ÇetinkayaMÖMehmet Özgür Özates

Key Points

  • The study aims to evaluate serum endocan levels following spinal cord injury and its correlation with injury severity.
  • Conducted an experimental spinal cord injury model in rats.
  • Measured serum endocan levels post-injury.
  • Correlated endocan levels with histopathological assessments of injury severity.
  • Serum endocan levels increased after spinal cord injury.
  • A positive correlation was found between serum endocan levels and the severity of histopathological changes.
  • Results suggest potential use of serum endocan as a biomarker for endothelial dysfunction in secondary injury.

Abstract

Serum endocan rises after experimental SCI and correlates with histopathological severity, suggesting its potential as a biomarker of endothelial dysfunction in secondary injury. Further studies are needed to evaluate prognostic value.

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Cite This Study

Kullukçu et al. (2026) studied this question.

synapsesocial.com/papers/69d0adc2659487ece0fa444chttps://doi.org/10.1080/01616412.2026.2654517
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