This research aims to examine the molecular changes in different layers of corneas affected by keratoconus.
Utilized spatial transcriptomics to analyze corneal tissue samples
Identified molecular alterations across various corneal layers
Investigated intercellular communication patterns in keratoconus samples
Revealed specific molecular changes in the layers of corneas affected by keratoconus
Demonstrated altered intercellular communication patterns associated with cone formation mechanisms
Abstract
Findings regarding the corneal layers and the intercellular communication patterns in KTCN corneas allowed for further understanding of the cone formation mechanism.