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April 5, 2026Scientific ReportsOpen Access

SoleFusion-Net: an explainable multimodal deep learning framework for diabetic foot syndrome classification in type II diabetes mellitus

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Authors

MSMehewish Musheer SheikhMBMamatha BalachandraDGDr Narendra G

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Overview

This framework demonstrates classification of diabetic foot syndrome using multimodal data, suggesting improved detection methods.

Key Points

  • To enhance early detection of diabetic neuropathy using an explainable deep learning framework.
  • Developed SoleFusion-Net integrating plantar pressure images and clinical data
  • Employed a late-fusion dual-branch architecture
  • Utilized convolutional layers for image analysis and tabular processing for clinical variables
  • Implemented explainability techniques like Grad-CAM and SHAP
  • Evaluated framework with 504 patients categorized into neuropathy severity levels.
  • Achieved 83% validation accuracy
  • AUCs of 0.962, 0.892, and 0.933 for mild, moderate, and severe neuropathy respectively
  • Identified vibration perception threshold and monofilament scores as key predictors
  • Demonstrated explainability through spatial analysis using Grad-CAM.

Cite This Study

Sheikh et al. (2026) studied this question.

synapsesocial.com/papers/69d1fd9ca79560c99a0a3c46https://doi.org/10.1038/s41598-026-42207-6
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