Abstract The purpose of this study was to examine the preventative and interventional effects of different fat sources (lard verses olive oil) and their respective lipid components in a Western-style high-fat diet and Mediterranean-style high-fat diet on tumor biology in vivo in a Cre-lox mouse model called iKAP (inducible Kras, Apc, p53) of colorectal cancer (Boutin et al, Genes thus, differences in tumor metabolism and growth remain a pertinent question. Citation Format: Cara C. Wallingford, Anindita Mahanty, Revan Hammontree, Alexa Magstadt, Jennifer Davis. Mediterranean versus Western diet - preventative and interventional effects of dietary lipids on colorectal tumor growth and biology abstract. In: Proceedings of the American Association for Cancer Research Annual Meeting 2026; Part 1 (Regular Abstracts); 2026 Apr 17-22; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2026;86(7 Suppl):Abstract nr 930.
Wallingford et al. (2026) studied this question.