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April 7, 2026Endocrine Metabolic & Immune Disorders - Drug Targets0 citationsOpen Access

Pathophysiology of CLD: Oxidative Stress and Antioxidant Mechanisms that may Limit its Progression

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PNPanagiotis Theodosis NobelosIPIoanna PapagiouvanniAPAdonis A. Protopappas

Key Points

  • The research aims to explore how addressing oxidative stress can affect liver fibrosis.
  • Review of pathways related to oxidative stress and antioxidants.
  • Analysis of current therapeutic strategies for liver fibrosis.
  • Integration of findings into potential clinical applications.
  • Targeting oxidative stress shows potential to reduce liver fibrosis.
  • Antioxidant mechanisms could reverse the progression of the disease.
  • Findings indicate promising pathways for clinical practice.

Abstract

In conclusion, targeting oxidative stress and its associated pathways represents a compelling strategy to attenuate or even reverse liver fibrosis, presenting a promising therapeutic strategy that could be integrated into clinical practice.

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Cite This Study

Nobelos et al. (2026) studied this question.

synapsesocial.com/papers/69d49fe5b33cc4c35a228579https://doi.org/10.2174/0118715303441513260220055400
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